The role of blood flow in glaucoma

Scientific literature and videos, made available and explained
by Katarzyna Konieczka, M.D., Ophthalmologist, Glaucoma Specialist

(0) Welcome to Swiss Glaucoma Research (
With a focus on vascular factors in high tension glaucoma and normal tension glaucoma
(1) Glaucoma more than just intraocular pressure
Glaucomatous optic neuropathy (GON), nerve fiber loss, optic disc excavation.
Visual disturbances, visual field defects, scotomas
Importance of intraocular pressure and ocular blood flow
(2) What do we know about blood flow in glaucoma?
Measurement of blood flow in glaucoma
What the studies with glaucoma patients show
Relationships between blood supply to the eye and that to other organs
(3) What are the causes of ocular blood flow disorder in glaucoma?
Intraocular pressure, blood pressure, perfusion pressure, retinal venous pressure (RVP), vasospasm, primary vascular dysregulations (PVD), Flammer syndrome (FS), arteriosclerosis
(4) Which mechanisms are involved in the development of glaucoma damage?
Impaired autoregulation, unstable blood flow, oxidative stress, astrocyte activation, endothelin, nitric oxide, optic nerve compartment syndrome, optic disc hemorrhages
(5) The vascular glaucoma concept by J. Flammer
How do the different risk factors and mechanisms interact in the development of glaucomatous optic atrophy?
(6) Holistic glaucoma therapy
Reduction of intraocular pressure, reduction of retinal venous pressure, treatment of arterial hypotension
Improvement of ocular blood flow regulation, reduction of oxidative stress
(7) Further professional information
Automatic perimetry, visual field indices, Bebie curve, Octopus program G1
Other aspects of Flammer syndrome
(8) Contact and dedication
To whom can patients, referring physicians and researchers address themselves?
Thanks to Josef Flammer, Prof. Emeritus